Risperidone Risperdal Side Effects, Interactions, Uses, Dosage, Warnings
Risperidone Risperdal Side Effects, Interactions, Uses, Dosage, Warnings
: :23-12-23, 12:56 sáng |
Risperidone Risperdal Side Effects, Interactions, Uses, Dosage, Warnings |
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Along with its needed effects, risperidone (the active ingredient contained in Risperdal) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. In addition, heat exposure may damage medication delivery devices and may degrade medications. EpiPens may malfunction or deliver less epinephrine when exposed to heat. Insulin, which should be stored in a refrigerator, may become less effective if left in the heat. Overall, each antipsychotic has its combination of benefits and side effects. Interactions that can make your drugs less effectiveClinical monitoring of weight is recommended during treatment. Infants exposed to RISPERDAL® through breastmilk should be monitored for excess sedation, failure to thrive, jitteriness, and extrapyramidal symptoms alcohol withdrawal symptoms timeline and detox treatment (tremors and abnormal muscle movements). Possible risk factors for leukopenia/neutropenia include pre-existing low white blood cell count (WBC) and history of drug-induced leukopenia/neutropenia. FDA warning: Increased risk of death in seniors with dementiaThe tablet will quickly dissolve and can be swallowed with or without liquid. Your doctor may give you a lower starting dosage of 0.5 mg taken twice per day. They pcp addiction signs, treatment, and prevention may increase your dosage more slowly to reduce your risk for side effects. If these effects are mild, they may go away within a few days or a couple of weeks. Risks and side effectsIn clinical trial and/or postmarketing experience, events of leukopenia/neutropenia have been reported temporally related to antipsychotic agents, including RISPERDAL®. Pooled data from three double-blind, placebo-controlled schizophrenia studies and four double-blind, placebo-controlled bipolar monotherapy studies are presented in Table 2. When fluoxetine or paroxetine is co-administered with RISPERDAL®, the dose of RISPERDAL® should be reduced.
The effect that symptomatic suppression has upon the long-term course of the syndrome is unknown. Given the primary CNS effects of risperidone, caution should be used when RISPERDAL® is taken in combination with other centrally acting drugs and alcohol. RISPERDAL® M-TAB® (risperidone) Orally Disintegrating Tablets are etched on one side with “R0.5”, “R1”, “R2”, “R3”, or “R4” according to their respective strengths. RISPERDAL® MTAB® Orally Disintegrating Tablets 0.5 mg, 1 mg, and 2 mg are packaged in blister packs of 4 (2 X 2) tablets. Consult your pharmacist or local waste disposal company. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Moreover, second-generation antipsychotics have agonism at the 5HT1A receptor. Serotonin and norepinephrine reuptake inhibition are potential mechanisms by which risperidone is postulated to produce antidepressant effects. The improvement of positive symptoms is thought to be accomplished through the blockade of D2 receptors, specifically in the mesolimbic pathway. The ability of antipsychotics to block D2 receptors in the prefrontal cortex and nucleus accumbens is important in improving certain psychiatric symptoms. Of note, risperidone does not cause anticholinergic effects, which may benefit patients in certain populations, including the elderly with dementia. Other drugs may interact with risperidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Risperidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. While many of risperidone’s side effects are manageable, others may be serious and, in rare cases, life-threatening. If you experience mild side effects when taking this medication, speak with your healthcare provider. If your side effects are life-threatening, seek medical care immediately or call 911. Some neonates recovered within hours or days without specific treatment; others required prolonged hospitalization. Patients with an established diagnosis of diabetes mellitus who are started on atypical antipsychotics, including RISPERDAL®, should be monitored regularly for worsening of glucose control. Any patient treated with atypical antipsychotics, including RISPERDAL®, should be monitored for symptoms of hyperglycemia including polydipsia, polyuria, polyphagia, and weakness. Patients who develop symptoms of hyperglycemia during treatment with atypical antipsychotics, including RISPERDAL®, should undergo fasting blood glucose testing. In some cases, hyperglycemia has resolved when the atypical antipsychotic, including RISPERDAL®, was discontinued; however, some patients required continuation of anti-diabetic treatment despite discontinuation of RISPERDAL®. There is no body of evidence available from controlled trials to guide a clinician in the longer-term management of a patient who improves during treatment of an acute manic episode with RISPERDAL®. As with all medications, any side effects must be considered in each individual case, not least because some people find certain side effects so disturbing that they would prefer a different treatment, despite the benefits. Using Risperdal Consta with other drugs that make you drowsy can worsen this effect. High doses or long-term use of risperidone can cause a serious movement disorder that may not be reversible. The longer you use Risperdal Consta, the more likely you are to develop this disorder, especially if you are a woman or an older adult. Neither clinical studies nor epidemiologic studies conducted to date have shown an association between chronic administration of this class of drugs and tumorigenesis in humans; the available evidence is considered too limited to be conclusive at this time. Pooled data from 7 placebo-controlled, 3-to 8-week, fixed-or flexible-dose studies in adult subjects with schizophrenia or bipolar mania are presented in Table 4. Risperidone comes as a tablet, a solution (liquid), and an orally disintegrating tablet (tablet that dissolves quickly in the mouth) to take by mouth. Drowsiness, dizziness, lightheadedness, drooling, nausea, weight gain, or tiredness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This is not a complete list of side effects and others may occur. It may take up to several weeks before your symptoms improve. There is now a broad range of antipsychotic medications available. ‘Atypical’ antipsychotics include risperidone, olanzapine, quetiapine, aripiprazole, amisulpride, ziprasidone, and paliperidone. These medications are effective but some have concerning side-effects, such as weight gain and other effects on body function. Risperdal (generic name risperidone) is an antipsychotic drug prescribed to treat schizophrenia, bipolar disorder and some behavioral problems in children with autism. It works by changing the effects of chemicals in the brain. For males, it may result in decreased sexual ability, inability to produce sperm, or enlarged breasts. If you develop any of these symptoms, tell your doctor right away. Taking Risperdal with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. The dose may be adjusted at intervals of 24 hours or greater, in increments of 1 mg per day. The effective dose range is 1 mg to 6 mg per day, as studied in the short-term, placebo-controlled trials. In these cocaine overdose: symptoms and prevention trials, short-term (3 week) anti-manic efficacy was demonstrated in a flexible dosage range of 1 mg to 6 mg per day [see Clinical Studies]. RISPERDAL® doses higher than 6 mg per day were not studied. |
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